Big Pharma

I'd like to direct some attention to this article volunteered to the Freakanomics crew at the Times.  Much thought on big pharma is biased in one or another way: Are pharmaceuticals effective or just cheap? Are they cheap? Do the companies behind them overstate their effectiveness? Do the diseases they supposedly treat even exist? Are we over-prescribed? and on and on.  It is best to hear some thoughts, pro and con, from the people deeply involved in the industry.